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Leibniz Institute for Age Research - Fritz Lipmann Institute (FLI) E.V.
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Type of institution
Biomedical research on mechanisms of ageing and age-associated disease
The FLI devotes its research activities to the molecular mechanisms of age-associated diseases and of senescence. Understanding such mechanisms may ultimately help to prevent or delay the development of disease with age. Based on the expertise of the research groups basic research predominates, however attention is also directed towards knowledge transfer to medical application, to prevention and therapy.
Main research areas
In the section "Cellular and organismic senescence", the stability of the genome and of telomeres, the epigenetic regulation of genes, and the identification of new genes involved in ageing are investigated. In the section "Specific age-associated diseases", mechanisms leading to protein folding diseases (e.g. amyloidoses, Alzheimer's disease, Huntington Chorea) and other neurodegenerative diseases, as well as mechanisms causing organ dysfunction (e.g. kidney failure, osteoporosis, immunosenescence) and cancer are analyzed. Disciplines of research: Molecular and cellular biology, genetics, structural biology, bioinformatics, biophysics, biochemistry, genomics and animal research.
Prof. Dr. Peter Herrlich, Director
Beutenbergstr. 11D-07745 JenaGermany