Browse Ageing Research Programmes

You are browsing data that matches the following criteria. Click the cross in any box to remove that search criteria.
Funder/CentreGerman Research Foundation (Deutsche Forschungsgesel...
Programme:Cellular mechanisms of Alzheimers's disease (SPP 10...
Hide ▴

German Research Foundation (Deutsche Forschungsgesellschaft)

Show all funders/centres
  • Research Programmes
  • Research Projects

Need some help?

If you find yourself getting a bit lost, try using one of the links below to get back to the beginning:

  • Go back to the start page
    You can search the whole database for specific search terms, choose a country or browse by category.
  • Perform an advanced search
    Useful when you know what you're looking for, and where the data might be stored.
  • Browse all Research Centres and Funders
    See a list of all centres from where you can view details and the programmes and projects that are associated with that centre/funder.
  • Browse all Research Programmes
    See a list of all the research programmes in the database. When you look at one you will automatically see which Research Funder/Centre it belongs too, and you can explore this programme's projects or see other programmes within the same funder/centre.
  • Browse all Researchers
    Individual researchers are not "attached" to any particular project or programme. If you want to narrow down the list you could choose a country on the start page and look at the list on the left of the page..
Cellular mechanisms of Alzheimers's disease (SPP 1085)Research Programme

Website

http://www.tu-darmstadt.de/fb/ch/Fachgebiete/OC/AKSchmidt/spp_main.html

Programme type

Research programme

Programme status

Ongoing

Total number of funded projects

15

Summary of key aims

Alzheimer's disease (AD) is characterized by the invariable accumulation of senile plaques, neurofbrillary tangles, and inflammatory processes. These pathological events are involved in the fatal neuronal cell observed in the brains of the patients. At lease five gene products (B-amyloid precursor protien, tau, Presenilin-1, Presenilin-2 and apoE) play a pivotal role in the pathogenesis of AD. It appears that miss-sorting and/or miss-function of these proteins is directly involved in amyloid plaque formation as weel as the accumulation of neurofibrillary tangles. Therefore a detailed understanding of the cell biology of these proteins and their cellular function will pave the way to understanding the patthological mechanisms causing AD. This may also help to identify novel targets for theraputic treatment. This program is therefore aimed to combine the efforts in cell biology and AD research and to provide a network within these two disciplines.

Management contact

Astrid Golla
Astrid.Golla@dfg.de
+49-(0)228-885-2824
Kennedyallee 40
53175 Bonn
Germany

Scientific contact

Christian Haass
chaass@med.uni-muenchen.de
0228/885-1
Ludwig-Maximilians-Universitat Munchen
Schillerstrasse 42/44
80336 Muchen
Germany

Funding contact

Deutsche Forschungsgemeinschaft
postmaster@dfg.de
0228/885-1
Kennedyallee 40
53175 Bonn
Germany

Is the project externally evaluated?

Yes

Who has evaluated, or will evaluate, the programme?

Reviewers

What forms of international collaboration does the programme support?

  • ▪ Foreign collaborators working in their own countries
  • ▪ Travel for foreign collaborators
  • ▪ National researchers abroad
  • ▪ Travel for national researchers

Interdisciplinary research is a strategic priority...

  • For the programme ✔
  • For the funding agency ✔
  • Nationally ✔