Browse Ageing Researchers
Dr. Thomas Flatt
Centre for Human and Social Sciences, Spanish National Research Council, CCHS-CSIC
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University of Veterinary Medicine Vienna
Group Leader, Principal Investigator
Institute of Population Genetics
Department of Biomedical Sciences
Josef Baumann Gasse 1
Biology of Ageing / Biogerontology
Molecular Genetics of Aging in Drosophila
Endocrine/hormonal regulation of aging; insulin/IGF-1 signaling
Physiological and metabolic effects on aging; trade-off between reproduction and lifespan
Thomas Flatt has been a permanent Group Leader at the Institute of Population Genetics at University of Veterinary Medicine in Vienna since January 2009. His main research interest is in the biology of aging, life history evolution, and evolutionary physiology. A central focus is on understanding how hormonal signaling pathways (e.g., insulin, juvenile hormone, and ecdysone) affect the phenotypic expression and evolution of aging and trade-offs between reproduction and lifespan, immune function, and somatic maintenance. To address these problems Flatt combines the tools of evolutionary genetics, molecular genetics, and physiology in the fruit fly (Drosophila melanogaster) and closely related species. Flatt was born in Solothurn, Switzerland, and studied biology at the University of Basel. In 1994 he was awarded a long-term fellowship from the Swiss Study Foundation. He received his M.Sc. in population biology from the University of Basel in 1999, for work supervised by Prof. Stephen C. Stearns (Basel) and Prof. Richard Shine (Sydney). In 2004 he earned his Ph.D. in evolutionary biology from the University of Fribourg (under Prof. Tadeusz Kawecki). Between 2004 and 2008 he was a postdoctoral research fellow in Prof. Marc Tatar's laboratory at Brown University (Providence, USA), sponsored by the Swiss National Science Foundation and the Roche Research Foundation. He is a faculty member of the Vienna Graduate School of Population Genetics (Doktoratskolleg Populationsgenetik). He is also currently editing a book on the mechanisms of life history evolution (to appear at Oxford University Press in 2011) and serves as a deciding editor for the Journal of Evolutionary Biology.